What are your last two PSA results and the dates for each? How many of the biopsy cores were positive for PCa and what percent of each core was positive? How many cores had cribriform? Does the pathology report specify large or small cribriform pattern?

I think we were all scared and confused upon diagnosis. You are on the right track being on MCC to begin to get an understanding of what your diagnosis means, what the possible treatment options are and potential side effects for each as well as a perspective on the choices made by others and their reasons for them. I was diagnosed with Gleason 9 in many cores, cribriform and EPE so I have a pretty good idea of how one feels when the diagnosis is a very high risk PCa. Take a deep breath, relax and begin to read and ask as many question as you have.
Bill

I’ve been on ADT for nine years. In general, nobody would know I’m on it except I get hot flashes now and then. Yes, I do have to exercise. I walk the track across the street twice a day every day, a mile each time. I have to take bone strengtheners. I took Fosamax For six years a pill you take once a week and now I’m on quarterly Zometa infusions. I go to the gym 2 to 3 days a week to keep my muscles in shape. I’ve never had a fatigue problem because I do all the exercising, that is critical in order to beat the fatigue.

There are worse things than ADT like dying Yeung. I’ve had prostate cancer since I was 62, I had surgery 15 years ago and It came back 3 1/2 years later so they gave me an ADT shot and two months later radiation for 7 1/2 weeks. The radiation never bothered me. I went to work right after and never had a problem with it. I’ve had two more reoccurrences, but have been undetectable for the last 22 months. I’m just waiting till the current Treatment I’m on fails and I will then move onto the next one.

I never even realized how bad ADT was because that shot before radiation didn’t affect me at all, and I only had one of them.

Don’t be afraid of ADT it can give you many many years of progression free survival.

It wasn’t till 2 1/2 years after radiation that my cancer came back that I went on Lupron For 6 1/2 years and then Orgovyx for 2.5.

Cribriform can make prostate cancer very aggressive and you are already a Gleason nine. Holding off on ADT can really shorten your lifespan. You’re not only should be on ADT but your doctor will probably also want you on an ARSI like Zytiga or a Lutamide. That is recommended with aggressive Gleason nine. To minimize the side effects try to get your doctor to put you on Nubeqa. It is quite easy compared to the other drugs. Zytiga is just like taking super ADT and is very difficult for many people.