Just to let you know I was on actonel several months ago - and it really ruined my esophagas- had terrible reflux -could not swallow food - had to go to the ER and now take medication for this. Really bad the Drs. don't inform you of the horrible side effects of these drugs. I never had any gastro issues before this. Same thing with Prolia-terrible joint pain, bleeding gums and hair loss.