@davepurvis: Dave, I'd like to welcome you to Mayo Clinic Connect albeit under these difficult circumstances for you. I've also been treating for metastatic melanoma and understand everyone's journey with this disease is unique and unpredictable. It sounds as though you've been through some tough challenges.

I'd like to understand more about what you've been through and are facing now. I'm trying to understand some of the acronyms you've used; I believe SBRT is stereotactic brain radiation. Have you been told you are currently in remission or that you require additional treatment for lesions in the brain and/or lungs? If so, what treatment is being considered? Please tell me more about your current situation.