Ivermectin for Prostate Cancer? (Being studied)

Welcome, @badbrad. I moved your question about the use of ivermectin and other supplements to treat prostate cancer to this related discussion:
- Ivermectin for Prostate Cancer? (Being studied) https://connect.mayoclinic.org/discussion/ivermectin-for-prostate-cancer/

I encourage you to read the posts and resources shared in the discussion.

I see that you are looking into alternative therapies. There's a lot of information as well as misinformation circulating about ivermectin and its use as a treatment for cancer. Here's a clear and well-written article about repurposed drugs being researched for cancer.

- Separating fact from fiction: repurposed drugs in cancer treatment https://www.anticancerfund.org/en/blog/separating-fact-fiction-repurposed-drugs-cancer-treatment

Here's some guidance from Mayo Clinic experts that might help your evaluation of these therapies:
- Natural vs. safe: Why the two aren't the same https://www.mayoclinic.org/tests-procedures/complementary-alternative-medicine/in-depth/natural-vs-safe-health-remedies/art-20587690
- Mayo Clinic on use of ivermectin or other dewormers to treat cancer https://connect.mayoclinic.org/blog/about-connect/newsfeed-post/mayo-clinic-on-use-of-ivermectin-or-other-dewormers-to-treat-cancer/

I don’t think you have anything to lose - other than time; but Ivermectin will raise your liver enzymes to unsafe levels so please be sure to monitor those closely.
Would love to hear a positive report from you in a few months since so far most reports are anecdotal.

If you're leaning towards radiation, then I'd suggest considering "radiosensitizers" to weaken the PC and make it more susceptible to being destroyed by the radiation treatments.

Besides stopping testosterone replacement therapy 60 days before the start of my radiation (I had Gleason 4+3 unfavorable intermediate PC), I decided to use the following as radiosensitizers based primarily on information from pre-clinical studies (all amounts were daily dosages):
- two low dose aspirin pills (there's actually a phase 3 clinical trial currently going on for "Add Asprin" in the UK; quite promising)
- 1500 mg berberine
- 20 mg low dose Atorvastin
- switched my high blood pressure medicine to 80 mg extended release Propranolol
- 100 mg Doxycyline (I discontinued this after the first month due to stomach problems)

I've also read good things about Metformin as a radiosensitizer, but I didn't know that at the time of my radiation. I might have substituted Metformin for Berberine if I knew this earlier.

Best wishes!

kenk1962, the "Add Aspirin" clinical trial looks VERY interesting...
https://pmc.ncbi.nlm.nih.gov/articles/PMC5127874/.

Nobody is interested in promoting ivermectin when it's effective in vitro and in animals and they know it for so many years why human trials have not been done

There are human trials related to cancer and ivermectin or mebendazole. You can search for human trials currently underway here: https://clinicaltrials.gov/

Yes - thank you RetiredBoomer. Fortunately I had heard about that trial which formed the basis of me taking the two low dose aspirin tablets before the start of my SBRT radiation treatments.

Interesting sidenote: In my first radiation oncologist meeting I informed the nurse practitioner about my low dose aspirin as a radiosensitizer based on the encouraging preliminary information to date from the "Add Aspirin" trial. To my utter surprise, the nurse practitioner said, "Hummm...I haven't heard about that."

Gosh - we really have to be on our toes and assume responsibility as our own advocates.

This site doesn't show any ongoing trials for ivermectin

Hi all, wanted your feedback with ivermectin be using for treatment of cancer. Florida has started a new study to investigate the possible benefits. There is some positive evidence, and my oncologist agrees there needs more research. Was wondering what yours thought are?

@thomb22, I encourage you to read the comments shared in this discussion:
- Ivermectin for Prostate Cancer? (Being studied) https://connect.mayoclinic.org/discussion/ivermectin-for-prostate-cancer/

Also see this information:
- Mayo Clinic on use of ivermectin or other dewormers to treat cancer https://connect.mayoclinic.org/blog/about-connect/newsfeed-post/mayo-clinic-on-use-of-ivermectin-or-other-dewormers-to-treat-cancer/

You are wise to discuss this with your oncologist.