Hello everyone, I joined this group in early June and am grateful for the information and insights shared here. I'm finally adding my own questions to the conversation:

BACKGROUND: After six months seeing specialists regarding severe back pain, my father was diagnosed in May with inoperable Stage IV PDAC, spread to the liver. He's had 7 cycles of Folfirinox. The first few rounds were very difficult, but for the past two months he's been able to enjoy doing things, like going for walks and working in the garden. His CA-19-9 has steadily decreased from 1297 in June to 568 on September 8th.

He's had two CT scans: the first in April (in which his tumor was discovered), and another on July 17th. The second scan showed no growth or spread, though the tumor didn't shrink at all.

On September 8th, his eighth round of folfirinox was delayed due to elevated liver enzymes (AST, ALT and Alk Phos)

We're worried about the ramifications of delaying chemo, though I understand it happens sometimes for a variety of reasons.

QUESTIONS: If anyone here has had a similar experience with elevated LFTs, I'd be grateful if you could share your experience. Also, should we be asking my father's oncologist to consult with a liver specialist? Should we ask for more scans to make sure there aren't any blockages in the liver?

One other detail: he's in the Seattle area.

I'd appreciate any insights or resources to help us navigate this!

Thank you!