Steroid injections while on Prolia/Jubbonti

Posted by Maryann @mkoch, Aug 28 1:03am

Has anyone been in the situation where they had a Prolia or Jubbonti shot and a month later needed steroid shots in their hip or back? I read that it increases your risk of infection. Just wondering if anyone else has been in this predicament. After a month, 50% of the denosumab (Prolia or Jubbonti) is still in your system. I have airline tickets for a trip planned 6 months ago, otherwise I would wait longer than one month after my last injection.

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Profile picture for szark55 @szark55

My Dr said ALL steroids cause bone issues…I didn’t say infection.

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He is incorrect. Epidurals do not enter the blood stream as regular steroid shots and worse are the tablets.

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Profile picture for stress101 @stress101

You are correct for epidural injections do not enter the blood stream as oral tablets. They do not affect the bones. I just had two transforaminal steroid epidural injections. My spine doctor assured me there was no risk in increasing my osteoporosis risk of fractures. So, it depends on how and what kind of injections you receive. Mine were injected into the nerve endings to reduce my pain. My Dr here in Dallas is a specialist in a Spine Clinic and is a teacher of injections so i trusted his educated statement plus it is also stated in other medical sites.

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@stress101, would you mind telling me your doctor's name. I am in Austin, and might wind up looking for help elsewhere in Texas. Also, would you mind telling me a bit about your condition? I have severe lumbar stenosis and am curious about the transforaminal injections and whether they have helped you.

BTW, I was told that injections could affect bone in the immediate area if they are given frequently and at high doses (though I have no idea how to define "frequent" or "high dose"). But the bottom line is that they apparently don't affect bones systemically the way oral steroids do.

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