← Return to Post prostatectomy. 1st PSA at .30, 2nd PSA at .43, future prognosis?

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Profile picture for rlpostrp @rlpostrp

Sorry to hear of your news. My first thought is that you fell into the same category as me: “surgical margins.” We are part of the unlucky 10-20% where the urologist/surgeon failed to remove all of the cancerous prostate…he left some tissue behind in his attempt to preserve the neurovascular bundles that are necessary for sexual function. With your first PSA being so high, I venture a guess that he left A LOT of prostate tissue behind.
Like all of us, “what’s done is done.” Your urologist can’t take you back to the operating suite to “try again” to get rid of all of the tissue.
What was your pre-surgical biopsy Gleason Score? I could be wrong, but you sound like at least a 4+4=8. And…did your surgical pathology report document things like Cribriform glands, seminal vesicle invasion (one or both), bladder neck invasion, and anything else? It sounds like you have an aggressive form of cancer for your PSA to have been so high post-op as well as on your second PSA. And…
It is odd that your doctor thinks it is too soon for radiation. Another doctor “down the street” might think completely differently. Maybe you should get a different opinion, and from a large university based hospital
My doctor spoke of radiation immediately upon getting my surgical pathology report. I had not even had my first PSA yet. Two months later it was thankfully < 0.1 ng/ml, so he backed off talking more about radiation for now. My next one is in another 30 days. Good luck to you, I look forward to your reply.

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Replies to "Sorry to hear of your news. My first thought is that you fell into the same..."

Hi @rlpostrp ,

Are you working now with urologist or RO and MO ? My husband is in high risk group with unifocal EPE and one tiny spot of inconclusive margin (it is actually far from nerves ) so I worry about the first PSA. His PSA is ordered for 12 week mark, but we will test it at 6 weeks in local walk-in lab. I do not trust doctors one bit at this point ...

Thanks in advance