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Introducing Brinsupri - Dr Chuck Daley video

MAC & Bronchiectasis | Last Active: Dec 6, 2025 | Replies (21)

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Anyone understand ----
Since brensocabit targets neutrophils, if neutrophils are generally normal, does brensocabit still work?

Thanks!

Ling

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Replies to "Anyone understand ---- Since brensocabit targets neutrophils, if neutrophils are generally normal, does brensocabit still work?..."

Yes, it does. Having elevated neutrophils is not a requirement for taking the drug.

I asked Dr Daly if someone with eosinophilia (vs high neutrophils) would benefit from Brinsupra and he replied that the Alpine (I think that's the name) study showed this to be true. I haven't read the study, but it may be worth a look.