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Looking ahead after Tymlos: Reclast, Evenity or HRT?
Osteoporosis & Bone Health | Last Active: Jun 8 10:19pm | Replies (114)Comment receiving replies
@drsuefowler Yes our situations are similar! It seems that once your are past the golden 10 year mark of menopause that scares most of the Drs into saying no to HRT. We both will have some explaining to do to the endos!! I'm 67 and 18 yrs post menopause. I have taken the full dose of Tymlos since starting, and still have the heart racing issue after injecting. Finally figured out to get up about an hour early, inject, then go back to sleep and that seems to work. When I wake up for the day I feel like normal instead of being sluggish for an hour to hour and a half after injecting. I sleep through that stuff.
So far no ill effects from either the bioidentical estrogen or progesterone. I have a patch for the estrogen, 0.05mg, and change it once a week. So far it's been 1 week! I still have a uterus, and still taking Tymlos for another 4ish months. If they do work together, then all the better! I had either heard on a podcast or read somewhere the same thing about effects of these hormones on the osteoclasts and osteoblasts. I kept that in the back of my mind when the gyn Dr said at this point the HRT wouldn't have any effect on my bones. I'm hoping there is a little boosting power given to Tymlos. Is your estrogen a tablet or pill? If so, maybe going to a patch would help with dizziness? Bypass the digestive system?
My progesterone is 100mg capsule. So far no effects from that either that I can tell anyway. Possibly sleeping a little sounder, but still waking a couple of times a night. Fewer night sweats, but still get them. And it only has been a week, so I'm calling it a win, kind of, so far. What is the progesterone cream you were prescribed? I'd rather have that, I think, than take the capsule. I'd prefer to avoid anything that is processed through the liver, but the cream wasn't offered, so I now have a 90 day supply of the capsule. Is it comparable to your 50mg progesterone dose, or stronger since it wasn't helping sleep?
Here's to us both getting good results and trying not to miff too many endos in the process!😂
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@psmnonna, I wrote you yesterday, but somehow my whole note disappeared. I like your idea of taking Tymlos before getting up in the morning, then going back to sleep. Since I usually get up twice in the night to go to the bathroom, it would be easy to try. I have been taking it at bedtime, but I think that it may interact with progesterone. The night before last, I think I used too much progesterone cream. My blood pressure went down to 90/60 at bedtime. I decided not to take my Tymlos since it also lowers blood pressure. I slept really well that night for the first time in forever! I do want to continue taking my Tymlos, since I have a lot left and I want to build or maintain bone. Last night, I took the regular 50mg cream dose a couple hours before bed and Tymlos at bedtime. I only got 2 1/2 hours of sleep at the beginning of the night. I'll try to take my Tymlos when I wake up for the second time.
The problem with the progesterone cream is you are never sure if you got the right amount. Mine comes in a pump container. The night I took too much, for some reason not much came out when I pushed it, so I pushed it 3 times. I wasn't sure how much I got. It is compounded and a lot of physicians don't recommend that. It is not FDA approved. I also have a compounded 50mg capsule that I may try again. I think my physician wants me to increase to the 100mg like you are taking.
My estrogen patch is much weaker than yours, 0.014mg compared to .05mg. I like it and feel like it is the progesterone that is troublesome. I could be wrong. The estrogen has enlarged my breasts and they are sensitive. I also have leg pain, but that may well be from Tymlos. It's good to hear that you have some improvement with sleep and hot flashes and no negative side effects! Thanks for your response and please keep us informed on how you are doing.