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Looking ahead after Tymlos: Reclast, Evenity or HRT?
Osteoporosis & Bone Health | Last Active: Sep 20 9:57am | Replies (113)Comment receiving replies
@psmnonna, I am in a similar situation to you. My 3 endos and 2 PCPs told me not to take HRT. I am 74 years old, 20 years past menopause. I took 40 mcg of Tymlos for 9 months, then Forteo for 6 months. I am now back on a half dose of Tymlos. I am very sensitive to medication. I found a functional physician who was willing to prescribe bioidentical HRT. I do not want to take Prolia or Reclast. My endos will not be happy with me when I see them in October.
I have been on Menostar, 14 mcg bioidentical estrogen for almost a month. It took me 16 days to adjust to the dizziness it caused. Then I decided to try the progesterone. She gave me 50mg of progesterone in a capsule. Since it didn't help me sleep, she gave me a compounded cream. I am trying to get used to that. I think some of my problems with progesterone are because I am still taking Tymlos. From what I've read, they appear to do the same thing. I don't have a uterus, but I did have surgery for endometriosis in the past. My functional doctor thinks that I need to balance the estrogen. Apparently, progesterone can increase osteoblasts, while estrogen decreases osteoclasts.
I hope that you get very good results with your HRT. Thanks for posting and please keep us updated.
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@drsuefowler, your comment about the impact of estrogen and progesterone on osteo oclasts and osteoblasts is interesting. I hadn't heard that progesterone increases osteoblasts and estrogen decreases osteoclasts but it makes sense. My naturopath physician certified by N.A. Menopause Society, said that the BHRT may give me a small amount of gain and if it did, I would need to remain on the BHRT to maintain any small gains. My REMS Echolight scan showed an increase from spine t-score -3 to -2.6 over a 10-month period. I had also been taking supplements recommended by Keith McCormick. My CTX bone turnover was reduced by 80% from 688 to 138 over an 8 month period. I began taking BHRT at 67 lin July 2024 and have so far not fractured nor taken any OP medication, I wish to avoid, though I would not refuse it if things took a severe turn for the worse. I will have another CTX next week.