My migraines are a side effect of a medication I was taking because I also have Multiple Sclerosis. I was getting Botox and suddenly it just stopped working, still take topirimate every night but does that help? I feel like I just can’t get my words out or is that the MS, still have a pounding headache everyday, now we trying nurtec. Still feel the headache but not as intense, was thinking about asking about the infusion but what I’m reading it doesn’t sound like ANYTHING works:( MS sucks enough, migraines on top of it is absolutely miserable. If anyone has any suggestions, I’d greatly appreciate it..