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Even just three weeks of physical inactivity can trigger a noticeable muscle loss in someone who's on hormone therapy. You've got to maintain weight training (and cardio, for overall health) THROUGHOUT the period when you're on hormone therapy. For someone who hasn't been previously physically active, it's imperative to begin exercising at the same time you start on hormone therapy. Sooner is even better.

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Replies to "Even just three weeks of physical inactivity can trigger a noticeable muscle loss in someone who's..."

I slowly ramped up weight training over the last 6 years for health reasons. Now that my BCR PSA rise leads me to assume that it won't be long before I'm on ADT, I hope to continue & even increase weight training.

Besides the important effects on muscle & bone, I've been reading preliminary studies that say resistance training & HIIT helps to release mytokines (cytokines from the muscle) that can show the progression of cancer. If so this increases hope & motivation--and we need all we can get. Has this been discussed here?
https://www.nature.com/articles/s41585-021-00476-y