Thanks for your detailed reply. I also have ankylosing spondylitis. Pain is becoming a major factor for me, so, I need take some sort of action to try and make things better. But, recently, I've experienced a downward spiral negative domino effect in my life: loss job, multiple health issues, and spouse dealing with severe illness, etc. I know nothing is guaranteed of course, but the thought of taking a medication, which results in a new negative domino effect/new class of illnesses, makes me shudder. I did get a referral for physical therapy, which I hope will help things. All of this if course costs money, that I don't have. Life is rather bleak these days. Isn't there some drug that actually can "cause" a femur fracture? That sounds completely insane (taking a drug to prevent fractures that may actually cause fractures). Appreciate comments.