I was a low T guy at 257 and tested on Lupron at 3 months and my T was 2 and PSA undetectable. I go in for my first post tx test next week at 2 months. I did Lupron for 3 months then switched to Orgovyx for 3 months. Rule of thumb that I have heard is Lupron's half life is equal to the length that you took it and Orgovyx's half life is 25 hours. Post Orgovyx I had my first day of clarity after two weeks and it has gotten better every week since.