What would you do if PSA stayed at 0.15 after prostatectomy?

Got a question for the group if anyone is or was in my situation...I had my Rp in 2021.one year later psa went up to .45 .doctors sent me in for 36 rounds of radiation..2 yrs later slight increase in psa so went for a biopsy in the pelvic upper area and the biopsywasn't secssfull couldn'tget it tough area upper pelvic area.psma showed a tiny dot less than a half centimeter so doctors said let's watch it and did psma scan twice 4 monthsapart.my psa slowly started to raise after 1 yr it went up to .40 so the doctor gave me orgovyx with 6 weeks my psa went undetectable. 5 months on orgovyx and the doctor did another psa test and still undetectable. Add psa undetectable Now they want to blast it with radiation 5 rounds starting this Friday. If anyone is in the same situation I'd like to know how it turned out and what your experience was...tyia

The PC oncologist recommends avoiding antioxidants such as CoQ10 and turmeric until after the radiation therapy, reason being one doesn't want to protect cells when you are nuking them. I take about 10 g/day of turmeric that has about 2 g/day of bioavailable curcumin (piperine [pepper] and lipids help absorption through intestinal walls). I take it to (hopefully) decrease my risk of multiple myeloma. There are a number of brands, none regulated by the FDA; I take Qunol 1 gm tablets. Do they help? My plasma kappa curve has flattened but don't know if there is any cause and effect, or just chance. I don't have side effects, but some people do. https://pmc.ncbi.nlm.nih.gov/articles/PMC8464730/ https://pmc.ncbi.nlm.nih.gov/articles/PMC6429287/ https://pmc.ncbi.nlm.nih.gov/articles/PMC2820199/#:~:text=Alone%20or%20in%20combination%20with,%2C%20treatment%20or%20co%2Dtreatment.

We’re not doing the curcumin right now as we are preparing for salvage radiation.

TJ...thanks for the note. After surgery my PSA went down from 4.1 to about 0.08 . then started a very slow climb over 3 years to 0.14 , at which time I got 22 sessions of EBRT - external BM radiation therapy. No ADT as I asked the doctors about 6 to 7 times and he said no. During the 22 sessions of External being radiation, I didn't actually get my blood tested, but I am told that it bounces around like crazy. After the 22 sessions and after about two months, I had my first PSA test and that came down to 0.11 then 0.072 a month after that ( so three months now. ) . The PSA has a big lag time with EBRT . Sometimes she will not get peak kill off of cancerous cells for 6 to 8 months. This is what my doctor had told me. So immediately you will get lots of fluctuations followed up by which should be a steady decline in your PSA. Keep me in the loop of how you're doing. Very interested.

I had an RP And 3 1/2 years later, my PSA started rising, so I had to salvage radiation. 2 1/2 years later, my PSA started rising so they put me on Lupron. Went on for 7 more years With more reoccurrences and more drugs.

Two years ago, the PSMA pet scan showed a metastasis on my spine. Had it zapped with three rounds of SBRT radiation. My PSA has pretty much stayed Undetectable for the last 22 months.

That is the way they handle this, Zapping the metastasis that do show up. It is usually very successful. Unfortunately, when you’re undetectable, there’s no way to do a pet scan to see if there are more metastasis. I’m sure they’re going after the one they last saw In the hope that it will resolve your issue. The only way to find out is to stop taking Orgovyx And see if your PSA rises.