bayhorse: The physiatrist ( a medical doctor who specializes in musculoskeletal issues) who gave a steroid injection to me 9 months ago (for my back, now I need one for my hip so I can walk for my trip to the WWII Museum; I would never be able to walk through an airport or the massive museum with the condition my hip is in.) said it can depress your immune system, therefore making you more prone to getting an infection. But it only stays in your system for about 3 weeks so I just need to stay away from the grandkids (petri dishes of bacteria) and wait 3 weeks before getting a Prolia/Jubbonti injection, which also depresses your immune system. (Because I don't want a double whammy on my immune system.) My endocrinologist said the # 1 complaint/side effect she hears about Prolia/Jubbonti is bladder infections/uti. That would correlate with a depressed immune system not being able to fight off a uti shortly after being injected with this osteoporosis drug. So I guess I'll avoid my grandkids for 3 weeks after a steroid shot and avoid my husband for a few weeks after a Prolia injection. (add smiley face)