Should I try using TRIMIX while on ADT?

Posted by robertmizek @robertmizek, Jun 9, 2024

ATTN MODERATOR: I’m aware that there is another post here related to TRIMIX. I’ve gone through it and could not find an answer that applies to my situation. In light of that I hope you don’t mind me starting a new thread on this.

Here’s my situation: I’m 69 years old now and in arguably good health except for PCa. Was diagnosed with Gleason 6 prostate cancer in 2020. Opted for focal Brachytherapy. For mix of reasons unimportant for this discussion treatment failed and PCa came roaring back last year. Was diagnosed with stage three prostate cancer with lymph node involvement in December 2023. Had salvage robotic prostatectomy in January 2024 at Northwestern medicine in Chicago. Dr. Ashley Ross. Dr. Ross was able to remove the known cancerous lymph node but was unable to safely remove a cancerous obturator lymph node. Started Orgovyx and Zytiga April 2024. PSA is undetectable now. My medical team wants me to be on both of these for 24 months. I am currently undergoing 33 sessions of IMRT to the lymph node basin.

I’ve been reading that permanent penile atrophy can be a real problem while on ADT. I recently watched a YouTube video presentation by Dr. Mark Scholz of the prostate cancer research Institute that addresses this issue. He was just discussing the viability of Trimix injections to keep penile tissue healthy, even if there is no libido. The idea is that when ADT ends, libido may return and it may be impossible to regain function if too much atrophy has taken place. Speaking frankly, I have zero libido, but have found that with stimulation a 60% erection is possible. I don’t think anything is going on nocturnally though.

Before I reached out to my urologist or oncologist, I thought I’d propose it to the forum and see what opinions others with more experience have. Thank you for reading this and I wish you all well on your journey with PCa!

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Profile picture for robertmizek @robertmizek

Thank you for your thoughtful comment. I genuinely appreciate it. While I have lost all interest due to ADT and know that I’ll be on it for another 21 months I think that I either need to start “using it” or accept “losing it” permanently. Could you please share what brand/model has worked for you? I previously tried a non-medical device that used an electric motor to create suction and was far too aggressive with far too little control.

Thanks again and best wishes for a successful journey with PCa.

Jump to this post

I use bathmate" Hercules filed with warm water..much more comfortable.

REPLY

I use Trimix while on ADT to both keep the penis healthy and to maintain a close relationship with my wife. I also use a vacuum pump to keep the penis healthy. I use the combination of the two about three times a week, with the vacuum pump for 20 minutes at a time up to three times a week, as this gets used more often than the Trimix.

REPLY
Profile picture for florida11 @florida11

I use Trimix while on ADT to both keep the penis healthy and to maintain a close relationship with my wife. I also use a vacuum pump to keep the penis healthy. I use the combination of the two about three times a week, with the vacuum pump for 20 minutes at a time up to three times a week, as this gets used more often than the Trimix.

Jump to this post

Thanks for your comment. I stopped ADT almost 6 months ago and my testosterone is back to near low normal. I’m still using TriMix once a week for intercourse and eventually may just need Cialis and a constriction ring. Good luck to you on your journey.

REPLY

Most everyone seems to have excellent results with Trimix, but I experience a dull ache during the entire erection, so enjoying intercourse isn’t an option. Apparently this is a less-common drug reaction, so I have discontinued. I’m in my 9th month of Orgovyx and 4 months since completing radiation.

REPLY
Profile picture for jime51 @jime51

Most everyone seems to have excellent results with Trimix, but I experience a dull ache during the entire erection, so enjoying intercourse isn’t an option. Apparently this is a less-common drug reaction, so I have discontinued. I’m in my 9th month of Orgovyx and 4 months since completing radiation.

Jump to this post

It might be worth trying Bimix. It often has less pain.

REPLY
Profile picture for florida11 @florida11

It might be worth trying Bimix. It often has less pain.

Jump to this post

I had the same experience with TriMix and switched to “super BIMIX”. No ache and an excellent erection.

REPLY
Please sign in or register to post a reply.