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johndavis60 avatar

Bone scan vs PSMA PET scan

Prostate Cancer | Last Active: Sep 11, 2025 | Replies (7)

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They all produce false negatives to the extent that there can be micrometastases too small for them to detect, but PSMA-PET is the most sensitive of the three (and also, I think, the "noisiest").

So no scan or blood test will tell us we're cancer-free — that medical technology doesn't exist yet. The best they can tell us is "nothing has grown big enough to show up on our radar yet." 😕

(But that said, I think results from the multi-faceted STAMPEDE trial suggested that if your metastatic prostate cancer remains castrate-sensitive for 5 years, you have a high chance of having entered long-term remission
🤞).

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Replies to "They all produce false negatives to the extent that there can be micrometastases too small for..."

My MO ordered a CT scan, which I did yesterday. Waiting for results ….
From everything I read, a prostate cancer met by itself on the frontal bone is extraordinarily rare. Mets to the base of skull are also less common and usually appear for very advanced cancer.