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Bone scan vs PSMA PET scan

Prostate Cancer | Last Active: Sep 11, 2025 | Replies (7)

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Do PSMA pet scans commonly produce false negatives?

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Replies to "Do PSMA pet scans commonly produce false negatives?"

They all produce false negatives to the extent that there can be micrometastases too small for them to detect, but PSMA-PET is the most sensitive of the three (and also, I think, the "noisiest").

So no scan or blood test will tell us we're cancer-free — that medical technology doesn't exist yet. The best they can tell us is "nothing has grown big enough to show up on our radar yet." 😕

(But that said, I think results from the multi-faceted STAMPEDE trial suggested that if your metastatic prostate cancer remains castrate-sensitive for 5 years, you have a high chance of having entered long-term remission
🤞).