I’m 4 months in of pure pain … no quality of life … no pain if I stay perfectly still … I wish I could take back my life no one has any answers they say it’s one in a million that this has happened to me …. I had poison put in my body … I wish there was a fix to this pain … had zero pain before the infusion
People do get totally unrelated conditions, but I wonder how many of these conditions are caused by Reclast. I had Reclast aug of 2024. I’ve been sore, and stiff, tired, depressed for the last year. I actually started feeling less aching in muscles and bones August 2025, one year after the infusion. Now time for another Reclast infusion. Now, do I get a second and hope for the best? I’ve cancelled my appointment 3 times. I know all drugs have side effects, but feeling like i aged 10 years doesn’t make living much fun.
People do get totally unrelated conditions, but I wonder how many of these conditions are caused by Reclast. I had Reclast aug of 2024. I’ve been sore, and stiff, tired, depressed for the last year. I actually started feeling less aching in muscles and bones August 2025, one year after the infusion. Now time for another Reclast infusion. Now, do I get a second and hope for the best? I’ve cancelled my appointment 3 times. I know all drugs have side effects, but feeling like i aged 10 years doesn’t make living much fun.
As others have shared here, the fact so many felt fine before the infusion but have experienced musculoskeletal pain since makes for a cause and effect argument. For 18 months after my infusion, I have had flare ups that mostly involve my right leg and can last for weeks or even months. When the time came to have my 2nd infusion, I declined. I am hoping it will work itself out of my body but it has caused issues that will remain as I have not been able to be as active as before. The flareups have affected my quality of life and yes, have been depressing. It's a good sign that your pain is easing and maybe you can put off your decision for a bit longer. My Dr. calls it a drug holiday even though I only had one dose. I don't intend to take it again. I wish you the best.
In 2008 I took Fosamax for about 3 months. No GI issues but one day I could hardly put weight on my right leg. I had pain from the hip on down. I stopped taking the med and my chart was flagged to not have it again. Over all these years, my numbers didn't change that much-not good but not worse. Fast forward to 2023 and a worsening in my spine alarmed me. In January of this year I agreed to try Reclast after speaking with friends and family who had no issues. The infusion was fine then about 10 hours later I had extreme pain in my ribs, side and upper back, dizziness and fever. It subsided over the course of the next day and after several days I felt fine. About 2 months later, I began having a lot of musculoskeletal type pains in my leg, both knees and hand. It lasted about 3 months with varying degrees of discomfort then abated for about a month only to begin again recently. My Dr. said that about 40% of people have similar side effects. It has affected me in a way that I could not be as active as before-walking, hiking, even gardening sometimes is difficult. I'm not sure the trade off is worth it. I won't know until my next scan but am leaning toward not repeating this medication come January. Everyone is different but I wish I had known this before taking it as it affects my quality of life.
I took only 3 doses of Fosamax in June 2024. After the third dose I experienced excruciating pain from left hip to knee. It was diagnosed as iliotibial band syndrome. It disappeared after I stopped the Fosamax. I then began AlgaeCal plus Strontium and OsteoStrong exercises. 15 months later DEXA showed LS spine improvement from -4.1 to -2.9. Left femoral neck improved from -2.9 to -2.4 and left total hip from -2.6 to -2.0. Now my endocrinologist says, "Well, that's good but I want you to start Reclast." I am terrified of doing so since having such a bad outcome with Fosamax. Just this morning I messaged her to say "no." Thanks for posting your story. What did you end up doing?
I took only 3 doses of Fosamax in June 2024. After the third dose I experienced excruciating pain from left hip to knee. It was diagnosed as iliotibial band syndrome. It disappeared after I stopped the Fosamax. I then began AlgaeCal plus Strontium and OsteoStrong exercises. 15 months later DEXA showed LS spine improvement from -4.1 to -2.9. Left femoral neck improved from -2.9 to -2.4 and left total hip from -2.6 to -2.0. Now my endocrinologist says, "Well, that's good but I want you to start Reclast." I am terrified of doing so since having such a bad outcome with Fosamax. Just this morning I messaged her to say "no." Thanks for posting your story. What did you end up doing?
I've shared elsewhere here that I actually took Fosamax years ago for a few months and then had right leg pain, as you, hip down to my ankle. I could barely walk. I couldn't think of anything else that it could be so stopped the Fosamax and it abated. I informed my Dr. I would not continue. My bone density stayed pretty much the same (~-2.4 femoral neck/hip and -3.5 spine) for 10 years then in 2023 my spine numbers worsened to -3.8 and I researched what I should take. Friends and family were taking Reclast without issue so I decided to go with that, even knowing it was in the same class of drugs as Fosamax. When my Dr. ordered it, the pharmacy flagged it as contraindicated because my chart showed an allergy/reaction to the Fosamax. We decided to override it and do it anyway. I did all the things, Tylenol, hydration prior and the infusion itself was uneventful but about 10 hours later I woke up feeling I had been hit by a truck-rib, side and back pain, fever, dizziness. Those symptoms slowly went away over the next 24 hours but about 8 weeks later, I began with the right leg musculoskeletal pain again. It continues to flare up 18 months in and lasts for a month or two then stops. Related or not, now I have severe osteoarthritis in that right knee and seeing PT for exercises to strengthen my supporting muscles and hoping to avoid a knee replacement. For that, I did do one steroid injection but you can only do so many and it may worsen the OP. I take Calcium, Vitamin D and have added collagen peptides/fortibone powder to my daily routine as well as tumeric powder in foods and tumeric/ginger tea. I told my Dr. I won't be taking it again. I will have a DEXA next week as it's been 2 years and will see if any changes. It seems you are making good progress with your regimen. My point here is that if you had trouble with Fosamax, you may have trouble with Reclast as they are both bisphosphonates but there's no way to know and no way stop it once you have the infusion. I don't think anyone knows how long it stays in your system. Others here say even if you take something else, gains have to be locked in with Reclast so I am off meds for good I think. I wish you the best making a decision.
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I’m 4 months in of pure pain … no quality of life … no pain if I stay perfectly still … I wish I could take back my life no one has any answers they say it’s one in a million that this has happened to me …. I had poison put in my body … I wish there was a fix to this pain … had zero pain before the infusion
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3 Reactionsi encourage you to see an allergist/immunologist.
People get totally unrelated conditions
People do get totally unrelated conditions, but I wonder how many of these conditions are caused by Reclast. I had Reclast aug of 2024. I’ve been sore, and stiff, tired, depressed for the last year. I actually started feeling less aching in muscles and bones August 2025, one year after the infusion. Now time for another Reclast infusion. Now, do I get a second and hope for the best? I’ve cancelled my appointment 3 times. I know all drugs have side effects, but feeling like i aged 10 years doesn’t make living much fun.
-
Like -
Helpful -
Hug
3 ReactionsAs others have shared here, the fact so many felt fine before the infusion but have experienced musculoskeletal pain since makes for a cause and effect argument. For 18 months after my infusion, I have had flare ups that mostly involve my right leg and can last for weeks or even months. When the time came to have my 2nd infusion, I declined. I am hoping it will work itself out of my body but it has caused issues that will remain as I have not been able to be as active as before. The flareups have affected my quality of life and yes, have been depressing. It's a good sign that your pain is easing and maybe you can put off your decision for a bit longer. My Dr. calls it a drug holiday even though I only had one dose. I don't intend to take it again. I wish you the best.
-
Like -
Helpful -
Hug
4 ReactionsI took only 3 doses of Fosamax in June 2024. After the third dose I experienced excruciating pain from left hip to knee. It was diagnosed as iliotibial band syndrome. It disappeared after I stopped the Fosamax. I then began AlgaeCal plus Strontium and OsteoStrong exercises. 15 months later DEXA showed LS spine improvement from -4.1 to -2.9. Left femoral neck improved from -2.9 to -2.4 and left total hip from -2.6 to -2.0. Now my endocrinologist says, "Well, that's good but I want you to start Reclast." I am terrified of doing so since having such a bad outcome with Fosamax. Just this morning I messaged her to say "no." Thanks for posting your story. What did you end up doing?
-
Like -
Helpful -
Hug
1 ReactionI've shared elsewhere here that I actually took Fosamax years ago for a few months and then had right leg pain, as you, hip down to my ankle. I could barely walk. I couldn't think of anything else that it could be so stopped the Fosamax and it abated. I informed my Dr. I would not continue. My bone density stayed pretty much the same (~-2.4 femoral neck/hip and -3.5 spine) for 10 years then in 2023 my spine numbers worsened to -3.8 and I researched what I should take. Friends and family were taking Reclast without issue so I decided to go with that, even knowing it was in the same class of drugs as Fosamax. When my Dr. ordered it, the pharmacy flagged it as contraindicated because my chart showed an allergy/reaction to the Fosamax. We decided to override it and do it anyway. I did all the things, Tylenol, hydration prior and the infusion itself was uneventful but about 10 hours later I woke up feeling I had been hit by a truck-rib, side and back pain, fever, dizziness. Those symptoms slowly went away over the next 24 hours but about 8 weeks later, I began with the right leg musculoskeletal pain again. It continues to flare up 18 months in and lasts for a month or two then stops. Related or not, now I have severe osteoarthritis in that right knee and seeing PT for exercises to strengthen my supporting muscles and hoping to avoid a knee replacement. For that, I did do one steroid injection but you can only do so many and it may worsen the OP. I take Calcium, Vitamin D and have added collagen peptides/fortibone powder to my daily routine as well as tumeric powder in foods and tumeric/ginger tea. I told my Dr. I won't be taking it again. I will have a DEXA next week as it's been 2 years and will see if any changes. It seems you are making good progress with your regimen. My point here is that if you had trouble with Fosamax, you may have trouble with Reclast as they are both bisphosphonates but there's no way to know and no way stop it once you have the infusion. I don't think anyone knows how long it stays in your system. Others here say even if you take something else, gains have to be locked in with Reclast so I am off meds for good I think. I wish you the best making a decision.
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