I’ve had two shots of Leqvio, with a third one scheduled in a couple of weeks. So far, I haven’t had any side effects.
I’ve seen people say that Leqvio doesn’t lower Lp(a), but I think part of the confusion comes from expectations. If someone starts with very high Lp(a), then even a 30% drop might not feel significant to them—yet it’s still a real improvement.
Here are my own results, comparing before Leqvio vs. after Leqvio:
Lp(a): 115.2 → 63 (41% decrease)
LDL: 106 → 63
Apolipoprotein B: 93 → 75
Triglycerides: 67 → 53
VLDL: 13 → 12
HDL: 56 → 68
Total Cholesterol: 206 → 143
For me, the changes have been very positive overall.
I should mention I also use a systemic .05 estradiol patch that also lowers Lp(a) and I take a 10mg Pravastatin