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What experience has anyone had with the Signatera blood test?
Bladder Cancer | Last Active: 2 days ago | Replies (110)Comment receiving replies
@ Holly: excellent!
@ ronzee50: excellent! I still have old tests showing as pending and canceled from 2024-12. Good thing you called.
@ 141emp: It is good that signatera helped early detection and that EVP is working. It is interesting you did not receive adjuvant preventative nivo based on checkmate 274 after adjuvant GC (and that they opted for GC instead of DDMVAC). Did you draw a signatera after RC and before starting GC? Hopefully you can finish a few EVP cycles and then switch to just maintenance pembro for two years. Signatera before RC should become standard of care: sadly it is not yet. You could potentially boost pembro with akkermansia, CBM588, camu camu, Claritin/Zyrtec, morning infusions (chronotherapy), exercise and intermittent fasting.
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Thank you and sorry for delayed response. I had switched doctors after by 2023 Turbt and my current Dr strongly advocated for Signatera. The first was before RC using the tumor from the previous surgeons turbt, second immediately after RC before chemo and then every 3 months during chemo and the following surveillance period. My medical oncologist did additional testing on the tumor before I started chemo and the plan was based on that. Sorry I don’t recall what those tests were. He’s the director of the genitourinary oncology & research program at my cancer institute . He did additional testing after Signatera became detectable this spring. I almost qualified for a new clinical trial , but had not been off chemo from last year long enough. I’ve just completed 5 of 6 cycles Evp with another Signatera and pet scan to follow. He’ll propose the revised plan based on results.