I have been completely transparent with my primary and neurologist that while I appreciate a conservative stance, I am not medically illiterate and simply do not have time to wait for for someone to get funding in this environment for full blown double blind human studies. In my case, I am 75 so time is critical. The multiple international longitudinal studies, NIH animal studies, and anecdotal evidence are good enough for me to give it a go. I am starting with 3 mg and intend to go to 5mg. Normal dosage for bipolar is 300-600 mg. So a 5mg dose is not a loaded gun providing I monitor eGFR and TSH levels- and both tests are a BAU part of my semiannual physical.

My diagnosis after NeuroPsych testing, specific blood work including genetic testing, and other imaging diagnostics are collectively termed Cognitive Impairment at this point. If I am to avoid the fate of so many in my family, I am availing myself of every option to slow the Alzheimer’s train. It is an extremely low dose supplement. If people were dying from it, we would know. I am trained in Neurophysiology so am confident if something goes south, I will recognize that. While I would prefer to partner with my Docs in this endeavor, I am nonetheless proceeding.

Thanks very much for your interest

I will report back.