I am a Galleri failure story 🙁

The Galleri test's sensitivity is different for different types of cancer, but for pancreatic cancer (PDAC) I hear it's not the best. If positive, you probably have cancer; if not, it doesn't mean you don't.

After Whipple surgery to remove a tumor from the head of my pancreas (and also remove gall bladder and duodenum and lymph nodes), the surgeon declared me clean. Less than 4 months later, MRI and rising tumor marker (CA19-9) suggested the main tumor was coming back fast. Biopsy couldn't find it and Galleri didn't detect it. Tumor board decided to do another MRI in 6 weeks, by which time it was too late -- confirmed metastatic.

I have zero medical training, but waiting 12 months for another CT is crazy. I'd ask for 3-month intervals until you see how much the nodules are changing in that interval, to establish a "rate of change" baseline for future scans. If there's no change after two 3-month intervals, then it's probably a very slow-grower -- maybe not as big an issue to expand the watch interval after that.

But similarly, depending on where the nodules are (what type of cancer it might be), see if you can find out what tumor markers would identify it, and try to get regular blood tests for them. Example markers for different cancers are PSA, CEA, CA19-9, CA125, CA72, etc. These are usually pretty cheap, and you could repeat them every month to get your current baseline and identify changes in the future.