Just wanted to share some information that I found on Chat AI which was somewhat positive regarding my PSA situation after radiation. I put in the question of having a 5.3 PSA after radiation, clean Pet Scan, no cancer detected in lymph nodes per MRI, if that would suggest cancer is still present. AI gave the following answer:

1. What’s expected after prostate radiation?
After radiation therapy, the prostate gland (and any cancer cells in it) are damaged gradually over time.
Unlike surgery (where the whole prostate is removed and PSA should drop close to zero quickly), radiation does not immediately eliminate PSA.
The PSA can decline slowly for 12–24 months after radiation. This slow decline is normal and is called the PSA nadir (the lowest level you eventually reach).
Sometimes the PSA even fluctuates or has a “PSA bounce” within the first year or two, which does not necessarily mean recurrence.

2. Why is your PSA still 5.3 after 3 months?

If your PSA before radiation was high, it often takes many months for it to come down significantly.
A level of 5.3 at 3 months is not automatically a sign of persistent or spreading cancer—it could just mean your prostate is still releasing PSA while the tissue (cancerous and normal) is being gradually destroyed.
Doctors usually don’t judge radiation success at the 3-month mark. They look for the long-term trend (6, 12, 18 months).

When I typed in my where my PSA was prior to radiation this was the reply:
Your PSA timeline so far

Before radiation: 8.4

3 months after radiation: 5.3
👉 That’s about a 37% drop already. This is reassuring, because the PSA is moving in the right direction.

📉 How this compares to expectations

At 3 months, many men still have PSA in the 4–8 range, especially if they started above 8.

A clear MRI and PET scan strongly suggest there isn’t detectable cancer outside the prostate.

The key is whether your PSA keeps trending downward at 6 months, 12 months, and beyond.

🔮 What’s likely ahead

6 months: You might see it in the 3–5 range (though there’s variation).

12 months: Often below 2–3, but it depends on how your prostate tissue responds.

18–24 months: Many men reach their nadir (lowest point), often < 1.0–2.0, though some land higher and still do well.

✅ Bottom line

Your PSA drop from 8.4 → 5.3 in just 3 months is actually a good sign.
It doesn’t mean there’s cancer outside the prostate — it means your radiation is doing what it’s supposed to, and we just need more time to see the long-term trend.

Just thought I would share this information from AI. Not advocating for AI, just found the information refreshing and interesting, and maybe you will too.