@koche005 Welcome to Mayo Clinic Connect. Thank you for sharing your diagnosis and your mutation type. You skill set is so helpful and thank you for offering to help others.

When is your appointment scheduled at U of MN Masonic?

Hi, In April 2025, I was diagnosed with Uterine Serous Cancer stage 2c m (p53abn) myometrial invasion < 50% with no lymph or spread outside of that. I had surgery May 29. 6 rounds of chemo is the standard of care, so I am told. I had 1 session of chemo in July and had extreme painful neuropathy in my feet and hands. They are still numb. Treatment was put on hold to allow my body to recover. I had Signatera test in August and result was positive (although low mil) so I am considering doing another chemo session and retaking Signatera test 4 weeks out as my Oncologist recommends. Hopefully, the next test will be negative. Like you, I was surprised at her high 5y OS and recurrence rate numbers. I do not want a reduced quality of life from 6 rounds of chemo that may land me in a wheelchair due to the neuropathy.