Stopping Nubeqa and Orgovyx after 6 months

If you have a bone lesion that means your cancer has already spread outside the prostate and it’s probably in your bloodstream. That means it can pop up anywhere. You really should be on ADT For a lot longer than six months if you’ve already had spread. This is something you really need to discuss with your doctor and your Gleason score is very important when it comes Deciding how long you should be on ADT.

They have pills for nausea. When I was put on a PARP Inhibitor they also included pills for nausea because it was a common issue. Speak to your doctor about this they can probably come up with a solution.

The Mayo Clinic would be amazing but I live in Canada so I assume that the costs would be exorbitant for us. I hear references to Centres of Excellence, so often, in videos, etc. There are positives to our Canadian Health Care system... we aren't paying for the ADT, etc. but the down sides are that it is a public health system. Wait times are atrocious. And, we kind of get what we get in terms of physicians and surgeons, unless it is something which is not required.

Thank you!
A little more background on my situation. I have been treated at UCLA Medical Center and am seeing a Genito Urinary oncologist there. I have also gotten a second opinion from a Genito Urinary oncologist at MD Anderson. Both docs well known and highly respected for their positive outcomes.
I think that their suggestion (both of them) that I might be best served by a holiday after 6 months of ADT is a real balancing act. I am meeting with them both in two weeks to really dive into my options and whether I might opt for this holiday. Testosterone deprivation is not a benign treatment and I think that more and more specialists realize that ADT can most certainly shorten life-expectancy in itself, and most definitely have a real negative effect on quality of life. I suffer from major brain fog, fatigue, irritability, anemia, significant joint pain, low white blood cell count, hot flashes that interfere with my ability to get quality sleep and a resting heart rate that has risen significantly. And yes, I ride my Peloton 3-4 times a week and do resistance training 2-3 times a week. I can’t imagine how I would be feeling if I did not do this.
Obviously, I consider all of these side effects better than dying from próstatas cancer, but I do think that forward thinking oncologists are now thinking that “holidays” from ADT, rather than just putting men on this toxic protocol for years and years on end, might be a more beneficial approach overall.
I am not sure how I will proceed but at least they are giving me this option. More specifically the option of taking a holiday and then monitoring my PSA closely to see if it rises above 0.1 and then possibly reapplying ADT or some form of radiation (based on PET Scan). I was hoping that someone else in this group had taken this path, but at this point I have not seen that response. Soooo, if I decide to take this ADT holiday, I will certainly let you all know how it goes. Good luck to you and keep fighting the good fight.

I'm a Gleason 9 with no spread on PSMA. In my initial consult with a radiation oncologist at Moffit Cancer Center I expressed a desire to minimize ADT. I completed Brachytherapy and IRBT and was "allowed" to stop my Orgovyx at 6 months.

I've wondered how aggressively your system would treat a 65 yr old with Stage 4? I hear, for instance, that in England some late stage cancers in younger seniors simply don't get the treatment pre-seniors would. Is that true in Canada?

BTW, my grandfather was from PEI and my daughter lives in Newfoundland. So, best wishes AND cheers from The States!

Thanks, Jeff, and yes, a bone lesion on a rib means out and running freely. My doc said I'd be on my ADT for 2-3 years. I was just interested in hearing a different opinion, if he got one. I'm taking Zofran, with limited success. I'll see my doc next Monday and I'll raise that issue.

How long have you been off?

How long have you been off?