So far, I have not noticed a difference with Kevzara since I have only been on it 2.5 weeks. I wish I could offer I better input. My experience with Prednisone withdrawal was that I went down 1mg per week starting from 20 mg. At 15 mg the pain and fatigue set back in. At 10mg the pain was do-able but constant and at 8 mg the pain was not tolerable. I am now back to 12 mg. The fatigue is brutal. But, again, I am early days with Kevzara. I do not intend to titrate down for at least another month.