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Sophie93 avatar

How bad is a spine T-score of -4 ?

Osteoporosis & Bone Health | Last Active: Sep 5, 2025 | Replies (63)

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Sophie, I was diagnosed with severe osteoporosis a year ago. My T score for my spine was -3.6. After 12 months of Evenity my T score was -3.5. I did everything possible from a high protein and calcium diet to walking 3 to 5 miles a day, lifting free weights and physical therapy twice a week for one whole year. I was told by my doctor that I’m in the 5% group where Evenity did not work for me. Not sure why, it could have been my own antibodies neutralized the drug, my thyroid disease or the osteoporosis was so severe when diagnosed that is was too late to turn it around. I’m on Prolia now and still maintaining my same routine of diet, exercise and prayer in hope of a lower score come 2026. I pray that you will have a better outcome than me.

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Replies to "Sophie, I was diagnosed with severe osteoporosis a year ago. My T score for my spine..."

It amazes me how some drugs work for others and then not for some. I did really well on Evenity went from -4.6 to -3.3. Then went on Prolia and basically had nothing went to -3.2. I was also on hormones during the time I was on Evenity and maybe that helped also.

You don't mention it so I assume you were not on a bisphosphonate prior to the Evenity? If you were, that might explain the lack of improvement while on Evenity. If not, I am sorry to hear that it didn't work for you.

I am on Evenity now but I took Fosamax for over five years. I stopped 15 months before starting on Evenity but I know the Evenity may not work as well for me because of the years of Fosamax.