I'm a Gleason 8 also with Cribriform 4 but PSMA PET scan on top of MRI revealed no metastases. So that's different from yours and I'm fortunate. My treatment is 6 mos of Orgovyx plus Abiraterone with ablative radiation just about midpoint to destroy the offending gland. Assuming all goes well and I continue to demonstrate no signals of escape, I should be good to go.

I certainly relate to your concern and what I read here as well as elsewhere seems to indicate ongoing ADT. So I would explore this topic with your doctor and not hesitate to get a second opinion! The good doctors always welcome second opinions especially if they come from a known and respected source. Usually just your medical records and permission are all that's needed.

The other comments here about the side effects resonate (!) frickin hot flashes, intermittent mental fog, fatigue. What a trip.