← Return to PSA/MRI not too bad, Biopsy not too good. What??

Discussion
jeff1963 avatar

PSA/MRI not too bad, Biopsy not too good. What??

Prostate Cancer | Last Active: 5 days ago | Replies (34)

Comment receiving replies
Profile picture for phildphs @phildphs

You want to be very careful here. I am 77. I have been on AS for 21 years at a top 5 prostate hospital. About 15 biopsies until 2025 have always been 3+3 or a few times negative. Due to a PSA in the 20s a biopsy was done June 2025 which showed all 3+3 except in one area three samples of 3+4 with less than 5% pattern 4 with no large cribriform. The PSMA was clean. I wanted to continue with AS but the hospital refused and instead recommended 28 radiation treatments. I went to another top 5 prostate hospital to see if it would continue me on AS with my 3+4. The new hospital obtained my biopsy sample and had its pathologist, fellowship trained at a leading institution, examine it. He read the sample as 3+3 !!! The urologist at the new hospital recommended AS and offered, but didn’t recommend as necessary, a Decipher test if it would make me feel more comfortable continuing AS. I requested it although I don’t think it is necessary. We do not yet have the Decipher result.

Jump to this post


Replies to "You want to be very careful here. I am 77. I have been on AS for..."

great info, thank you! You were diagnosed at about the same age as I was. 21 years of AS is amazingly great, I had hoped to get many more years myself.

It will be interesting to see what next steps are recommended by my Mayo Team, but seems like a PSMA would make sense for me.

Glad you have done well all these years and hoping your Decipher results are good news. Once you get the Decipher results, please share here if you would like.

Thanks, again!

Actually, the PSE test could be more important than a decipher test. The PSE test Is 94% accurate in telling you whether or not you do have prostate cancer. You have had a lot of biopsies, but it’s designed to prevent biopsies if it doesn’t find prostate cancer.

If it does find it, then treatment is important.