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Your highest Gleason score was 4+3, so you are a Gleason seven 4+3. The other numbers don’t really matter as far as doctors are concerned.

A Gleason seven is slow growing, so waiting a month is not really a problem for most people. The fact that you’re going to Mayo, and at the Rochester clinic, gives you the best chance of really good treatment. The only problem you mentioned, from your biopsy, is cribriform. It can be very aggressive. You want to find out if it was large or small cribriform. If it’s small, then surgery can remove it pretty easily along with the prostate, And it’s also treatable with SBRT radiation. . If it’s large, it’s very aggressive and may require surgery and radiation Or a combination of a couple of different types of radiation. My brother had small cribriform, It was specifically mentioned in his biopsy. He had SBRT radiation and that seems to have handled all of his prostate cancer issues.

At this point, they normally want you to see a urologist first, And they will talk about surgery. After that, you meet with the radiation oncologist to discuss radiation. You do have two options. How old you are is important. If you are in your 60s, it might make more sense to have surgery since you could have radiation if that cribriform causes a problem after treatment. They do say that surgery and radiation have the same long-term results so you do have both options to consider. Listen to the doctor carefully when you go to them to find out what the best treatment would be for your specific case. Make sure to emphasize the cribriform As a potential serious problem.

It would make sense to get a Decipher score to see if there is a chance of reoccurrence. Cribriform can make that score higher, It would be really helpful to find out what your long-term chances are.

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Replies to "Your highest Gleason score was 4+3, so you are a Gleason seven 4+3. The other numbers..."

I'll be 77 in December.
I communicated with the Mayo referring NP yesterday, inquiring about the cribriform & Decipher. (I've not seen an MD urologist at Mayo; I went to Mayo on my own w/o a urologist referral because no one in Kansas City was doing the transperineal biopsy w/o anesthesia that Mayo performs. My Kansas City urologist wanted to do a transrectal biopsy w/o first doing an MRI. I had to talk this urologist into ordering and MRI & it showed 2 PIRADS 5 lesions, one of which was an anterior lesion that might not have been caught during a standard grid transrectal biopsy.) The Mayo referring NP indicated that because of the cribriform he could order a PSMA PET scan at Mayo, which would be useful to have prior to my meeting with the oncologists. (Again, one has to wonder why the patient is the one who needs to initiate such matters. The Mayo NP discouraged me from having this PET scan done in Kansas City. [We have a National Cancer Institute Designated Comprehensive Cancer Center here]) He further indicated that when I have my consults with the Mayo oncologists they may want to do a Decipher test.
Thanks for your prompt response to my query. I appreciate this & your numerous other informative posts on this forum.