← Return to Has anyone gone off hormone therapy (ADT) after radiation?

Discussion
Comment receiving replies
Profile picture for gkgdawg @gkgdawg

My husband's Gleason score was 7 (4 plus 3). According to the PSMA , he has about 5 cancer spots in his lymph nodes. He has never ad hot flashes. He says he thinks he has brain fog; in the morning it takes a bit to kind of clear his head. According to a blood test last week, his testosterone is less than .2. Same with his PSA. Biopsy in Sept 2024 said left base prostatic adenocarcinoma Grade 4. Rt. middle zone prostatic cancer Group 2, 3 +4; Cribiform absent Intraductal Absent, Cancer 3/23 cores . Periprostatic fat absent. cancer 3 % of all core tissues. The urologist said that we had caught it early; no worries. The earliest we could get to an oncologist was 6 months later. By that time, we had an MRI and paid for our own PSMA - The PSMA showed Metastases to left internal iliac/perirectal lymph node; Right internal iliac lymph node by vas deferens; Enlarging 14mm internal iliac/right pelvic sidewall lymph node; Enlarging right junctional iliac lymph node; Right external iliac lymph node; common ilic lymph node; left common iliac lymph node; retroaortic triangular lymph node; elongate left pelvic sidewall/internal iliac lymph node; left junctional iliac lymph node metastesis. He has been on Elegard (first injection May 15 2025); and Abiraterone and Prednisone June 1st. .

Jump to this post


Replies to "My husband's Gleason score was 7 (4 plus 3). According to the PSMA , he has..."

Sorry, but what you are describing does not sound like it was ‘caught early’. It’s in multiple lymph nodes - that is much later than you would like.
I think he will be on ADT for quite some time.
Phil

@gkgdawg

This addresses a question I have also: if the spread is beyond the oligometastatic number of 5 in the pelvic lymph nodes (only or can other lymph nodes count?) you've lost the option for a possible long remission (cure) with radiation, along with ADT?
If this isn't the case, and there are too many lesions, then the only option is 18 mo's of ADT and ARPI to indefinite use of ADT/ARPI?