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← Return to Prolia discontinuation
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Osteoporosis & Bone Health | Last Active: Dec 19, 2025 | Replies (206)
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Because there is clinical data does not mean that the doctors we are seeing have read and understand that. I think I surprised one when I told her Prolia is out for me as I can not risk any reduction in my immune system. I have a stable blood cancer and low globulin count. Any infection could be very serious for me.
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to @normahorn
Yes, it was just wishful thinking about doctors being familiar with latest research indeed. Depression of immune system is really serious problem with Prolia, and I would be very careful about it with your diagnosis. Interestingly, many years before I studied effects of bisphosphonates (BP) on immune system in rabbits and rats. It appeared that BP also depressed immune system. Somehow medicines influencing bone metabolism have effects on immune system.