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Can anyone share their experience with Pluvicto?

Prostate Cancer | Last Active: Sep 25 5:56pm | Replies (241)

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I'm 83, had prostate removed on 2001, been on hormone therapy since then, also immune therapy, Xteva and now Pluvicto. I've had 3 injections with the only noticeable side effect was a dry mouth for about a week. After the 4 th injection the dry mouth has persisted for 3 weeks, not bad but taste is off a bit. I've been hiking between 5-6 miles a couple of times a week, kayaking and biking 20 miles.Somewhat fatigued but still able to participate. I read that the dry mouth could persist for awhile or even become permanent. I've been very fortunate my PSA went from 8 to .05 after 3 injections. Stopped the Xtandi after the 3 injection and next week will see what blood levels are. Since stopping Xtandi BP has dropped, hope to get off some BP meds.

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Replies to "I'm 83, had prostate removed on 2001, been on hormone therapy since then, also immune therapy,..."

The dry mouth side effect can persist for a while and can even be permanent, though for my husband it isn't severe. He finished Pluvicto in August of 2024.

Staying on an ARSI can be very important. Xtandi Does cause fatigue for a lot of people, Nubeqa (Darolutamide) On the other hand, doesn’t normally cause fatigue and also doesn’t pass the blood brain barrier so it doesn’t cause brain fog,

You should ask your doctor about getting on Nubeqa, It can be important for a long-term progression free survival.