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Methotrexate side effects

Polymyalgia Rheumatica (PMR) | Last Active: Sep 22 3:00pm | Replies (45)

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I was diagnosed with PMR in July 2024 and Sjogren's Syndrome in December 2024. I also have MS which has been in remission.
Presently I am taking 5 mg prednisone daily and 6 Methotrexate pills once a week. My question is: Besides the MTX side effects of nausea, fatigue and diarrhea which thankfully now they only last for a day or so, I have pain in my arms, legs and sometimes a headache (almost like a PMR flare), does anyone else experience the pain part?

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Replies to "I was diagnosed with PMR in July 2024 and Sjogren's Syndrome in December 2024. I also..."

@relaxedphd
I’m sorry you are going through all this.

I had methotrexate infusions for a short time, and it affected my lungs. I developed ground glass opacity. It cleared up when I stopped the infusions.

Blessings

Hello @relaxedphd,

I combined your discussion on methotrexate side effects with a previous discussion of yours on the same topic:

"Methotrexate side effects"
- https://connect.mayoclinic.org/discussion/methotrexate-side-effects/

Here, members can see your new post and question and have a chance to comment and reconnect with you.