I had amikacin iv Three times a week at the infusion center and it took about an hour. I don’t know where you live so may be there is no infusion center nearby. Also I flushed the picc line myself on days off amikacin and the nurse on the day on the med with heparin so not to get blood clots. Dressing was changed and blood for kidney and liver function was drawn once a week at the infusion center.