← Return to Prolia infusion and BE flare afterwards

Discussion
desertdwellerjh avatar

Prolia infusion and BE flare afterwards

MAC & Bronchiectasis | Last Active: Sep 25 11:05am | Replies (39)

Comment receiving replies
Profile picture for bee1950 @bee1950

Thank you for this discussion. I am undecided about Prolia which was recommended recently by an endocrinologist. I have had osteoporosis for 20 yrs, and more recently injected Forteo for 2 yrs. I am 75 diagnosed with bronchiectasis & MAC nearly 8 yrs ago after hemoptysis landed me in the hospital. I have been very fortunate as the regular hemoptysis ended after I started nebulizing 7% sodium chloride. What worries me most about Prolia is it “may increase your risk of developing infections” . So far I have stayed mostly well on this 8 yr. journey! I’d welcome the experience or comments by any others who have taken Prolia. I am a Mayo patient & will be sending a note to my pulmonary Dr. this week. Take care all. Linda

Jump to this post


Replies to "Thank you for this discussion. I am undecided about Prolia which was recommended recently by an..."

I’m am the same situation, finding an osteoporosis med that will not interfere with my BE, which is pretty well controlled. Any info would be helpful.

@bee1950 I am 81, in 4 months will be 82. I was bullied into taking Prolia starting in September 2021. Diagnosed with breast cancer in May 2022. I had to take an aromatase inhibitor because my breast cancer was hormone driven, they would have put me on one of the biphosphonate drugs anyway. I am 5 years out from starting Prolia and until my first infusion of this year in March I have not to my recollection had any infection after a Prolia infusion but in March this year, 1 week after my injection, I started having the worst seasonal allergies reaction I have ever had. I have coughed til my ribs are sore. Much better 8 weeks later. I dont know for a fact that Prolia had anything to do with it or not but I am suspious that it did. I was diagnosed with very slight BE and MAC last summer. No symptoms at all. Saw an ID last summer and because I have no symptoms they decided not to treat the MAC at this time. Had my second bronchoscopy in November 2025 and the culture grew nothing after 8 weeks. I usually dont have seasonal allergy symptoms after May. So I guess I will find out if the MAC is rearing its ugly head or not. I wish I had NEVER agreed to start Prolia because I am told I will have to take it the rest of my life. Had a bone density scan a couple weeks ago. Don't know my numbers. Will call and ask but they did say my spine is osteopenic and my hips which were osteoporotic on scan 2 years ago are now osteopenic. Not sure if thats improvement in my hips or not but have a call in to nurse to ask for numbers. I wish you well. If I had a do over, I would fight tooth and nail NOT to take ANY of the drugs for osteoporosis because of the possible awful side effects that are proven to happen. A friend had 2 spontaneous fractures after Fosamas. Her femur then 10 years later her pelvis. She died 5 days after her first Covid injection in January 2021.🥹