Thank you for this discussion. I am undecided about Prolia which was recommended recently by an endocrinologist. I have had osteoporosis for 20 yrs, and more recently injected Forteo for 2 yrs. I am 75 diagnosed with bronchiectasis & MAC nearly 8 yrs ago after hemoptysis landed me in the hospital. I have been very fortunate as the regular hemoptysis ended after I started nebulizing 7% sodium chloride. What worries me most about Prolia is it “may increase your risk of developing infections” . So far I have stayed mostly well on this 8 yr. journey! I’d welcome the experience or comments by any others who have taken Prolia. I am a Mayo patient & will be sending a note to my pulmonary Dr. this week. Take care all. Linda