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Wife will complete 12 Folfirinox treatments. It has not determined if she is stage 3 or 4. Oncologist has delayed biopsy indicating Folfirinox would be the treatment for either stage. Suspicious spots on liver but no biopsy until full chemo is completed. What is your opinion of NanoKnife for either stage 3 or 4 (liver involvement) and is SBRT a better approach than conventional radiology after completion of chemo?

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Replies to "Wife will complete 12 Folfirinox treatments. It has not determined if she is stage 3 or..."

Thank you for your question, and I understand how difficult and complex this situation must feel. Your oncologist is correct that the initial treatment course would typically be the same regardless of final staging. The goal is to assess how the disease responds to systemic chemotherapy before making decisions about local therapies like surgery or radiation. I recommend continuing to work closely with your oncology team at a high-volume pancreatic cancer center to fully explore and understand your options. Best wishes to you and your family.