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Reducing from split dose - reduce night or morning?
Polymyalgia Rheumatica (PMR) | Last Active: Aug 30 10:58pm | Replies (12)Comment receiving replies
Taking it all in the morning closely mimics your natural hormone release cycle. Many people think they need to even out the dose throughout the day based on the fact that the steroid dose packs have you take it that way. These are the packs that come 6 pills on day 1, 5 pills on day 2, 4 on day three, etc. Taking steroids evenly throughout the day is not mimicking your natural release of steroids. My best, Reader's Digest advise it to take the 1.5 mg in the morning so your body has the best chance of adjusting to a natural rhythm.
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I'd agree with you at higher doses. With our body's normal cortisol production being the equivalent of around 5mg prednisone, I assume that at 2mg prednisone with no adrenal insufficiency symptoms like fatigue and lowered blood pressure, my own cortisol production has probably resumed.
Some people have flares even at this late stage so I want to avoid that. I was a bit twitchy about reducing the early evening dose because it has done so well so far at keeping morning pain away. I'm thinking now that that may not matter any more. Currently reducing .5mg from the 1mg early evening dose. Fingers crossed.