I don’t think it matters if you can go to sleep and stay asleep without waking up in the middle of the night with pain. I lost half of a night of sleep because of so much pain at 3 a.m.

A single dose all in the morning isn’t supposed to cause as much adrenal suppression . I’m not sure if that is true or not. I took moderately high doses of prednisone for such a long time that my endocrinologist expected my cortisol level to be low after 12 years on prednisone. She expected my adrenal function would be poor no matter if I split my dose or not. She added it would be better when I reached a low dose of prednisone to take it all in the morning. That might help me recover my adrenal function sooner.