I also am a DES Granddaughter with multiple autoimmune disorders as well multiple cancers. My AI ranges from PsA, AS, RD, RA, HD. I carry an MSH2 gene mutation that causes Lynch Syndrome and multiple cancers...so far, ive had metastatic uterine cancer, metastatic breast cancer, papillary thyroid cancer, squamous cell colon cancer, and currently Barretts Esophagus. My Mom, a DES Daughter also has AS, RA, RD and has had 7 types of cancer, now currently battling Stage 4 Kidney Disease.