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DiscussionReducing from split dose - reduce night or morning?
Polymyalgia Rheumatica (PMR) | Last Active: Aug 30 10:58pm | Replies (12)Comment receiving replies
Replies to "I've split mine with good results. My rheumy doens't know why and keeps asking my why..."
I don’t think it matters if you can go to sleep and stay asleep without waking up in the middle of the night with pain. I lost half of a night of sleep because of so much pain at 3 a.m.
A single dose all in the morning isn’t supposed to cause as much adrenal suppression . I’m not sure if that is true or not. I took moderately high doses of prednisone for such a long time that my endocrinologist expected my cortisol level to be low after 12 years on prednisone. She expected my adrenal function would be poor no matter if I split my dose or not. She added it would be better when I reached a low dose of prednisone to take it all in the morning. That might help me recover my adrenal function sooner.