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Jak Inhibitors for PMr

Polymyalgia Rheumatica (PMR) | Last Active: Aug 31, 2025 | Replies (20)

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I have genetic cholesterol issues. prednisone increased my cholesterol significantly. Be careful of the statins as treatment. They have their own issues with side effects. I think those of us lucky enough to be in this group all have some reactions to different medications. Zetia worked about the best with few side effects but the low dose of 10mg was not effective at reducing my total numbers. I switched to a rather expensive epi pen drug called Repatha. shot twice a month. It has dropped my total numbers and LDL in half. No side effects in 3 years. good luck with RINVOQ

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Replies to "I have genetic cholesterol issues. prednisone increased my cholesterol significantly. Be careful of the statins as..."

Thankyou for that information regarding your treatment for genetic high cholesterol.Did you see a cardiologist ?

One of my daughters has the familial type of high cholesterol. She is the last person that you would suspect to have high cholesterol. I don’t know why it was checked when she was 16.

My daughter is adopted. She says how glad she is because she doesn’t have my genes. She has witnessed so many things that have happened to me. I don’t tell her that I’m worried about her genes too.

She stopped her statin once because I was talking about how my statin might be causing some problems for me. I didn’t mean she should stop her statin. Her cardiologist set her straight when her cholesterol level was over 300.