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Following RP in 2022, my 90 day post stop PSA was a persistent .19 (confirmed 30 days later at .18). Gleason 9 w/ EPE confirmed post-op by pathology.

I was referred to the Radiation Oncologist whose treatment recommendation was Salvage Radiation 37 IMRT of 1.8 gy, 66.6 GY total. to the prostate region, together with 25 of those treatments 45 GY to the pelvic lymph nodes, together with short-term ADT.

All of my treatment has been at Johns Hopkins.

My PSMA PET scan did not show definitive spread.

The SPORRT trial supports radiation to the whole pelvic region or WPRT. ADT appears to be a moving target with most receiving ADT, but not everyone.

My layman opinion after 3 years of treatment and reading on this journey is that salvage radiation treatment should include the pelvic lymph nodes and the entire region.

My uPSA has been undetectable at < .02 on quarterly testing for the past 2 years.

Best wishes.

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Replies to "Following RP in 2022, my 90 day post stop PSA was a persistent .19 (confirmed 30..."

Totally agree with @michaelcharles on this one. Just went thru similar treatment at Sloan. 6 months ADT with 25 radiation treatments, including pelvic nodes.
Your cancer is still there, nobody knows EXACTLY where it is no matter what test or scan you have.
I understand your fears about setting back your progress after surgery but please remember that you are dealing with cancer and it is a nasty adversary.
And an excellent radiation team - and your complete cooperation with treatment preparation - can mitigate/minimize many of the side effects you are concerned with. Best,
Phil