← Return to The lowest effective dose, how is it defined?

Discussion
Comment receiving replies
Profile picture for gmdb @gmdb

If you drop your dose below the level required to eliminate the inflammation from the PMR, then inflammation will build up again and pain will result. The steroids don't cure the PMR, just control the symptoms. And, like you, I don't think methotrexate does much good for the majority of us. So really we are taking the steroids for relief while waiting for the PMR to go away.

The risk is that if you drop the steroids too fast and too low that the level of inflammation that builds up will need an even higher dose of steroids to get rid of it and then you get into a yo-yoing pattern of going up and down. Small cautious steps in reducing dosage are the best way long-term. You are also at the level where your adrenal function needs to kick in and start carrying some of the load naturally so that can cause issues as well because that process can be very slow as well. It is a complex and very confusing illness to manage.

Jump to this post


Replies to "If you drop your dose below the level required to eliminate the inflammation from the PMR,..."

It is confusing. The Dr’s advice of going back to 5 mgs for a month then taper to 4 mgs, or the alternating days amount wasn’t exactly helpful as in what’s the best course of action? I wish I had quizzed him more thoroughly!
But I thank you for your response. It helps me understand a little more this new world I’m living in. Time for me to invest in a notebook to note daily details of mgs, pain levels, fatigue & energy levels.