@dreamer38 I normally waited a few days to make a change just to see if it was an overnight thing with the additional pain level. If the pain level didn't increase and it was tolerable I let it go another day to see if it would stay the same or get better. Some instances I found that the pain level decreased a little the next day. I'm sure it's different for each of us so it's something you just have to experiment with by making small changes up or down. My small was usually 1 mg or 1/2 mg prednisone. I found a good pill cutter and could cut the 1 mg tablets fairly easy.