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Alternative to PPIs?

Neuropathy | Last Active: Dec 9, 2025 | Replies (18)

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I’ve wondered the same thing as I have Barrett and esophagitis. I’ve been on Prilosec 4 months and G.I. doctors tell me to just stay on Prilosec ? Yet it’s possible harmful to body due to certain side effects. Apparently controlling stomach acid is main concern. Have you been able to stay off the PPI medicine and not have issues with acid reflux ?

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Replies to "I’ve wondered the same thing as I have Barrett and esophagitis. I’ve been on Prilosec 4..."

@jmedj55 there's really an art to going off the PPI. It has to be done on a slow taper or else you will get a rebound effect which is very unpleasant. I'm currently on a very slow taper which will take anywhere from 1 to 3 months. My doctor said it was okay to cut up my pills, even though you're not supposed to. The first few days were quite rough but I have an arsenal of helpful OTC items that are helping to get me through like alka-seltzer, Yogi Ginger tea, slippery elm capsules, and something I really like before laying down, Life Extension's Esophageal Guardian. The theory is that eventually the acid producing cells stop overcompensating, and things settle down, I hope.