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Lupron yeah or Lupron nay that is the question.
Prostate Cancer | Last Active: Sep 29, 2025 | Replies (112)Comment receiving replies
Run as fast as you can from Lupron or anything like it. These medicines are poison! You'll find in this blog that there are men who stopped Lupron as long as 7 years ago and are still experiencing horrific side effects. I convinced my care team to stop these injections after 9 months. Although some of the side effects have waned, I'm now facing osteoporosis and they (of course) want me to take other drugs. I few weeks ago I leaned over the soft arm of our sofa and broke a rib. Good luck and God speed.
Replies to "Run as fast as you can from Lupron or anything like it. These medicines are poison!..."
I do t believe this is the case for everyone. My husband was57 when he was diagnosed with prostate cancer, surgically removed, no chemo or radiation at the time. Lupron injections kept the cancer cells from multiplying for 30 years. He just passed away at the age of 88. I feel so fortunate that his doctors felt the need for lupron was greater than the annoying side effects it created.
Since we are all different and our cancer is unique, our treatments need to fit each individual’s cancer. That said, despite the numerous and awful side effects of Lupron, it does work for most people and does stop or slow the progression of prostate cancer. nine years ago I had prostatectomy due to a very small amount of Gleason 3+5 cancer near the capsule. After three years, my PSA became detectable and was going up. They gave me two months of daily radiation and six months of Lupron. The side effects of the Lupron were minimal and testosterone returned to 400 within three months with no residual side effects. After a couple of years, my PSA started to increase again and my PSMA PET scan showed a single lesion (oligometastic cancer) on my sacrum. It was radiated and I was put on Lupron and Abiraterone/Prednisone. For the next three years I had undetectable PSA and clean PSMA PET scans. Since the side effects were numerous and awful, I elected to go off ADT, at least until my PSA showed cancer again. That was ten months ago and I still have no signs of cancer. Unfortunately, I still have most of the side effects although my testosterone is slowly returning. Would I take Lupron again? Absolutely! I am living a wonderful , active life instead of dying of cancer.
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This is not good advice. I’ve been on ADT for nine years, It has kept me alive along with an ARSI (first Zytiga now Nubeqa). I’ve had four reoccurrences, but that’s kept it under control Even though I have the genetic problem of BRCA2, Which prevents my DNA from correcting errors.
I’ve been on bone straighteners for about eight years. If you go on ADT, you are supposed to go on bone strengtheners right away, According to a bone specialist, who gave a talk within the last year about ADT and bones.
Stopping ADT too soon can result in a shortened progression free survival. Not everybody needs it for a long time. If you have a high Gleason score, it can Extend your life significantly.